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Identification of Serum Biomarkers for Nasopharyngeal Carcinoma by Proteomic Analysis.

Authors :
Ye-Sheng Wei
Yan-Hua Zheng
Wei-Bo Liang
Jian-Zhong Zhang
Zhi-Hui Yang
Mei-Li Lv
Jing Jia
Lin Zhang
Source :
Cancer (0008543X). Feb2008, Vol. 112 Issue 3, p544-551. 8p. 1 Diagram, 3 Charts, 4 Graphs.
Publication Year :
2008

Abstract

The article focuses on a study which assessed the feasibility of mass spectrometry-based protein profiling for differentiating patients with nasopharyngeal carcinoma (NPC) from noncancer patients. The study analyzed serum samples from patients diagnosed with NPC and from noncancer controls using surface-enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI-TOF-MS). It concluded that SELDI-TOF-MS combined with a tree analysis model can discriminate NPC from noncancer patients.

Details

Language :
English
ISSN :
0008543X
Volume :
112
Issue :
3
Database :
Academic Search Index
Journal :
Cancer (0008543X)
Publication Type :
Academic Journal
Accession number :
30807317
Full Text :
https://doi.org/10.1002/cncr.23204