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Examining the living genome in health and disease with DNA microarrays.

Authors :
Diehn, Maximilian
Alizadeh, Ash A.
Brown, Patrick O.
Diehn, M
Alizadeh, A A
Brown, P O
Source :
JAMA: Journal of the American Medical Association. 5/3/2000, Vol. 283 Issue 17, Special Section p2298-2299. 2p. 1 Color Photograph.
Publication Year :
2000

Abstract

Focuses on the use of DNA microarrays to examine the physiology of the living genome. Information on DNA microarrays, including how they detect gene expression patterns, capture molecular pictures and deduce the condition of cells; How gene expression patterns can provide a detailed molecular picture of the pathogenic process; Implications for drug development in the discovery of disease-specific genes and pathways; Challenge of discovering the biological activities of proteins on a genomic scale.

Details

Language :
English
ISSN :
00987484
Volume :
283
Issue :
17
Database :
Academic Search Index
Journal :
JAMA: Journal of the American Medical Association
Publication Type :
Review
Accession number :
3052491
Full Text :
https://doi.org/10.1001/jama.283.17.2298-JMS0503-4-1