Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial.

The article focuses on research which examined probiotic prophylaxis in predicted severe acute pancreatitis. In the research 298 patients with predicted severe acute pancreatitis were studied. researchers found that in patients with predicted severe acute pancreatitis, probiotic prophylaxis with a combination of probiotic strains did not reduce the risk of infectious complications and was also associated with an increased risk of mortality. Researchers suggested that probiotic prophylaxis should not be administered in patients with predicted severe acute pancreatitis.