Synthesis of 2-(5-Substituted-1,3,4-thiadiazolo-2-ylimino)-4-thiazolidinones under Microwave Irradiation.

Fifteen 2-(5-substituted-1,3,4-thiadiazolo-2-ylimino)-4-thiazolidinones were efficiently synthesized from the reaction of ammonium thiocyanate with 2-chloro-N-(5-substutited-1,3,4-thiadiazolo-2-yl)acetamides under microwave irradiation. The target compounds were obtained in better yields (75-98%) and shorter time (5 min) than with conventional heating. [ABSTRACT FROM AUTHOR]