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Neutral networks of sequence to shape maps
- Source :
-
Journal of Theoretical Biology . Feb2008, Vol. 250 Issue 3, p484-497. 14p. - Publication Year :
- 2008
-
Abstract
- Abstract: In this paper we present a combinatorial model of sequence to shape maps. Our particular construction arises in the context of representing nucleotide interactions beyond Watson–Crick base pairs and its key feature is to replace biophysical steric by combinatorial constraints. We show that these combinatory maps produce exponentially many shapes and induce sets of sequences which contain extended connected subgraphs of diameter n, where n denotes the length of the sequence. Our main result is to prove the existence of exponentially many shapes that have neutral networks. [Copyright &y& Elsevier]
- Subjects :
- *NUCLEOTIDES
*NUCLEOTIDE sequence
*NUCLEIC acid analysis
*BIOPHYSICS
Subjects
Details
- Language :
- English
- ISSN :
- 00225193
- Volume :
- 250
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Journal of Theoretical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 28398031
- Full Text :
- https://doi.org/10.1016/j.jtbi.2007.09.012