An LC-MS-MS method for the comprehensive analysis of cocaine and cocaine metabolites in meconium.

Focuses on the development of a sensitive, precise, and accurate liquid chromatography-mass spectrometry method for the extraction of cocaine and other cocaine metabolites from meconium. Use of a solid-phase extraction method; Variation in the quantity and quality of the metabolites that were collected; Potential of ecgonine for testing neonatal cocaine exposure.