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Optical Tweezers as a Probe for Oligodeoxyribonucleotide Structuration.
- Source :
-
Nucleosides, Nucleotides & Nucleic Acids . Oct2007, Vol. 26 Issue 10-12, p1295-1299. 5p. 1 Diagram, 2 Charts. - Publication Year :
- 2007
-
Abstract
- The aim of this work is to investigate if the optical tweezers (OT) are suitable as a diagnostic tool for monitoring the oligodeoxyribonucleotide (ODN) structural behavior in solution. Preliminary experiments, performed on the quadruplex formed by the ODN sequence TGGGGT, showed that the OT can be used as a probe for ODN structuration by monitoring the medium viscosity changes associated with ODN folding-unfolding processes. [ABSTRACT FROM AUTHOR]
- Subjects :
- *DIAGNOSIS
*NUCLEOTIDES
*NUCLEIC acids
*BIOMOLECULES
*DNA
Subjects
Details
- Language :
- English
- ISSN :
- 15257770
- Volume :
- 26
- Issue :
- 10-12
- Database :
- Academic Search Index
- Journal :
- Nucleosides, Nucleotides & Nucleic Acids
- Publication Type :
- Academic Journal
- Accession number :
- 27754805
- Full Text :
- https://doi.org/10.1080/15257770701530541