Pharmacologie en oncologie pédiatrique: particularités.

Chemotherapy plays a key role in the treatment of cancer in children. Thanks to its efficacy, three out of four children can now be cured. Nevertheless, 25% of paediatric cancer patients go uncured, and chemotherapy-induced long-term side effects justify the continued development of new agents and strategies to fight childhood cancer, including the investigation of off-patent drugs, which are administered on a daily basis in paediatric oncology. In this context, we review the specific characteristics of children compared to adults and the reasons for expanding pharmacological research that focuses on paediatric oncology. Such research is now encouraged and supported by European legislation and new international organisations, such as the consortium, Innovative Therapies for Children with Cancer (ITCC). [ABSTRACT FROM AUTHOR]