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Female Mice Are More Susceptible to Developing Inflammatory Disorders due to Impaired Transforming Growth Factor Β Signaling in Salivary Glands.
- Source :
-
Arthritis & Rheumatism . Jun2007, Vol. 56 Issue 6, p1798-1805. 8p. 3 Black and White Photographs, 1 Chart, 3 Graphs. - Publication Year :
- 2007
-
Abstract
- The article focuses on a study aimed to delineate the precise function of transforming growth factor β (TGFβ) signaling in salivary gland inflammation. The TGFβ signaling in mouse salivary glands was impaired by conditionally inactivating expression of TGFβ receptor type I. The results suggested that female mice are uniquely more susceptible to developing inflammatory disorders due to impaired TGFβ signaling in their salivary glands.
Details
- Language :
- English
- ISSN :
- 00043591
- Volume :
- 56
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Arthritis & Rheumatism
- Publication Type :
- Academic Journal
- Accession number :
- 27556617
- Full Text :
- https://doi.org/10.1002/art.22715