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Clinical efficacy of a 308 nm excimer laser for treatment of psoriasis vulgaris.
- Source :
-
Photodermatology, Photoimmunology & Photomedicine . Dec2007, Vol. 23 Issue 6, p238-241. 4p. 2 Color Photographs, 2 Charts, 1 Graph. - Publication Year :
- 2007
-
Abstract
- Objective: To evaluate the efficacy and safety of a 308 nm excimer laser for the treatment of psoriasis vulgaris patients. Method: Forty subjects with psoriasis vulgaris (26 macular type, and 14 chronic plaque type) were treated by a 308 nm excimer laser. The initial dose was based on multiples of a predetermined minimal erythema dose, while the subsequent doses were adjusted on the response to the intervention, which was twice per week for a total of 15 treatments. The therapeutic efficacy and safety were then evaluated. Results: Of the 40 patients who received and completed the entire 15 times of laser radiation, (1) the Psoriasis Area and Severity Index score was improved by 90.19±10.12% and 77.34±17.04% in macular type and chronic plaque type, respectively ( P<0.05) and (2) the average treatment sessions were 13.7 times. The average cumulative doses for all patients were 6.86±2.48 J/cm2, in which it was 5.64±1.86 J/cm2 for macular type and 9.13±1.80 J/cm2 for chronic plaque type, respectively ( P<0.05). Conclusion: Our clinical data suggest that treatment of psoriasis vulgaris by a 308 nm excimer laser is effective and safe, and it is more efficacious in macular type than in chronic plaque type. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 09054383
- Volume :
- 23
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Photodermatology, Photoimmunology & Photomedicine
- Publication Type :
- Academic Journal
- Accession number :
- 27308117
- Full Text :
- https://doi.org/10.1111/j.1600-0781.2007.00317.x