Intrauterine Growth Retardation, Insulin Resistance, and Nonalcoholic Fatty Liver Disease in Children.

The article offers information on the results of a study on the association of nonalcoholic fatty liver disease (NAFLD) in children with intrauterine growth retardation independent of and in addition to insulin resistance. It says that small for gestational age (SGA) with NAFLD represent a subset with a higher prevalence of both metabolic abnormalities and Non-Alcoholic Steatohepatitis (NASH). It states that factors known to affect insulin sensitivity may also independently contribute to liver disease progression.