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Multiple safeguards against tumour development.
- Source :
-
Journal of Internal Medicine . Nov2007, Vol. 262 Issue 5, p505-508. 4p. 1 Diagram. - Publication Year :
- 2007
-
Abstract
- The author reflects on the various approach in protection against tumor developments. He stated DNA repair serves a dominating role in safeguarding against tumor growth but mismatch repair deficiencies and the consequent microsatellite instability may lead to multi-cancer syndromes. He said that intercellular surveillance is another powerful defense mechanism against tumor, which is based on the interaction between tumor cells and their host environment.
Details
- Language :
- English
- ISSN :
- 09546820
- Volume :
- 262
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Journal of Internal Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 27091255
- Full Text :
- https://doi.org/10.1111/j.1365-2796.2007.01859.x