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Substitution of His59 converts CD39 apyrase into an ADPase in a quaternary structure dependent...

Authors :
Grinthal, Alison
Guidotti, Guido
Source :
Biochemistry. 01/11/2000, Vol. 39 Issue 1, p9. 8p. 1 Diagram, 2 Charts, 20 Graphs.
Publication Year :
2000

Abstract

Discusses the effects of mutations in apyrase conserved region determined by whether they occur in intact tetrameres or in disrupted tetrameres or monomers. Result of substitution in tetrameres lacking either transmembrane domain and in monomers lacking transmembrane domains; Varied adenosine triphosphatase and adenosine diphosphatase mechanisms used by CD39.

Details

Language :
English
ISSN :
00062960
Volume :
39
Issue :
1
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
2707959
Full Text :
https://doi.org/10.1021/bi991751k