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Fluorimetric and mass spectrometric study of the interaction of β-cyclodextrin and osthole
- Source :
-
Spectrochimica Acta Part A: Molecular & Biomolecular Spectroscopy . Nov2007, Vol. 68 Issue 3, p474-477. 4p. - Publication Year :
- 2007
-
Abstract
- Abstract: The inclusion complex of β-cyclodextrin (β-CD) and osthole was studied by the electrospray ionization mass spectrometry (ESI-MS) and fluorescence spectrometry. From the mass spectrum, the 1:1 stoichiometric inclusion complex of β-CD and osthole was observed. The tandem mass spectrum was performed. The fluorescence intensity of osthole increased in the present of β-CD. According to the 1:1 β-CD–osthole mode, the dissociation constant (K D) was obtained by ESI-MS and fluorescence spectrometry. The K D of β-CD–osthole inclusion complex is 6.96×10−3 molL−1 obtained by mass spectrometry and that is 8.14×10−3 molL−1 obtained by fluorescence spectrometry, which is consistent with each other. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 13861425
- Volume :
- 68
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Spectrochimica Acta Part A: Molecular & Biomolecular Spectroscopy
- Publication Type :
- Academic Journal
- Accession number :
- 27001990
- Full Text :
- https://doi.org/10.1016/j.saa.2006.12.013