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Comparison of Effectiveness of Rosuvastatin Versus Atorvastatin on the Achievement of Combined C-Reactive Protein (<2 mg/L) and Low-Density Lipoprotein Cholesterol (<70 mg/dl) Targets in Patients With Type 2 Diabetes Mellitus (from the ANDROMEDA Study)
- Source :
-
American Journal of Cardiology . Oct2007, Vol. 100 Issue 8, p1245-1248. 4p. - Publication Year :
- 2007
-
Abstract
- Decreasing C-reactive protein (CRP) in addition to decreasing low-density lipoprotein (LDL) cholesterol may further decrease coronary heart disease risk. The effects of rosuvastatin compared with atorvastatin in achieving a combined target of LDL cholesterol <70 mg/dl and CRP <2 mg/L in 509 patients with type 2 diabetes mellitus was evaluated. CRP decreased significantly versus baseline in both treatment groups. Significantly more patients treated with rosuvastatin achieved the combined end point of LDL cholesterol <70 mg/dl and CRP <2 mg/L compared with atorvastatin by the end of the study period (58% vs 37%; p <0.001 vs atorvastatin). In conclusion, CRP was effectively decreased in patients with type 2 diabetes receiving rosuvastatin or atorvastatin, whereas rosuvastatin decreased LDL cholesterol significantly more than atorvastatin. [Copyright &y& Elsevier]
- Subjects :
- *TYPE 2 diabetes
*ISOPENTENOIDS
*ENDOCRINE diseases
*CHOLESTEROL
Subjects
Details
- Language :
- English
- ISSN :
- 00029149
- Volume :
- 100
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- American Journal of Cardiology
- Publication Type :
- Academic Journal
- Accession number :
- 26999265
- Full Text :
- https://doi.org/10.1016/j.amjcard.2007.05.044