Synthesis of Some New 3-Oxo-2-[(Z)-1-phenylmethylidene]-5H-[1,3]thiazolo[3,2-a]-and N-Acetylated Pyrimidines.

3-Oxo-2-[(Z)-1-phenylmethylidene]-5H-[1,3]thiazolo[3,2-a] pyrimidine derivatives 2a-f were synthesized by the reaction of an appropriate 3,4-dihydro-2(H)-pyrimidone 1, chloroacetic acid, sodium acetate and benzaldehyde. Reaction of 1 with acetic anhydride under heating afforded only 3-N-acetylated 3,4-dihydro-2(H)-pyrimidines 3a-f. The yields of the products after recrystallization from ethanol were of the order of 60-92 %. IR, 1H NMR spectroscopy, and elemental analysis were used for the identification of these compounds. [ABSTRACT FROM AUTHOR]