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Microcalorimetric study on the bacteriostatic activity of isoquinoline alkaloids.

Authors :
Liu, X. J.
Zhang, H. L.
Tan, Z.-C.
Han, K. L.
Sun, L. X.
Source :
Journal of Thermal Analysis & Calorimetry. Sep2007, Vol. 89 Issue 3, p907-911. 5p. 5 Charts, 8 Graphs.
Publication Year :
2007

Abstract

The isoquinoline alkaloids were isolated from traditional Chinese drugs of Phellodendri Cortex, Radix Stephaniae Tetrandrae, Corydalis Yanhusuo and Corydalis Bungeana. The power-time curves of growth of E. coli at different concentrations of isoquinoline alkaloid at 37°C were determined by a 2277 Thermal Activity Monitor. The rate constant of bacteriostastic activity was calculated. The relationship between growth rate constant and concentration was established. The optimum bacteriostastic concentration was determined. Experimental results have indicated that all the isoquinoline alkaloids isolated from the four kinds of traditional Chinese drugs have bacteriostastic activity and the order is Phellodendri Cortex>Radix Stephaniae Tetrandrae>Corydalis Yanhusuo>Corydalis Bungeana. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
13886150
Volume :
89
Issue :
3
Database :
Academic Search Index
Journal :
Journal of Thermal Analysis & Calorimetry
Publication Type :
Academic Journal
Accession number :
26391707
Full Text :
https://doi.org/10.1007/s10973-006-7606-2