Back to Search
Start Over
Microwave irradiation assisted synthesis, alkylation reaction, and configuration analysis of aryl pyrogallol[4]arenes
- Source :
-
Tetrahedron . Sep2007, Vol. 63 Issue 39, p9614-9620. 7p. - Publication Year :
- 2007
-
Abstract
- Abstract: A series of aryl pyrogallol[4]arenes were efficiently synthesized in excellent yields by cyclocondensation of pyrogallol with aromatic aldehydes under microwave irradiation. The structures of aryl pyrogallol[4]arenes were confirmed by characterization of their acylated derivatives. Under microwave irradiation, alkylation reactions of aryl pyrogallol[4]arenes with some alkylating reagents such as n-butyl iodide, benzyl chloride, and ethyl α-chloroacetate were also finished quickly to yield fully O-alkylated products. The 1H NMR spectra and crystal structures showed that the acylated and alkylated aryl pyrogallol[4]arenes existed mainly in rctt (cis–trans–trans) configuration. [Copyright &y& Elsevier]
- Subjects :
- *ARYLATION
*MICROWAVES
*ELECTROMAGNETIC waves
*ALKYLATION
*CHEMICAL reactions
Subjects
Details
- Language :
- English
- ISSN :
- 00404020
- Volume :
- 63
- Issue :
- 39
- Database :
- Academic Search Index
- Journal :
- Tetrahedron
- Publication Type :
- Academic Journal
- Accession number :
- 26248314
- Full Text :
- https://doi.org/10.1016/j.tet.2007.07.043