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Facile Synthesis of (±)-Paeonilide.
- Source :
-
Journal of Organic Chemistry . 5/11/2007, Vol. 72 Issue 10, p3952-3954. 3p. 2 Diagrams. - Publication Year :
- 2007
-
Abstract
- (±)-Paeonilide, a novel monoterpenoid metabolite from the roots of Paeonia delavayi showing anti-platelet activating factor activity, is convergently synthesized in five steps with 59% overall yield. The application of benzoyl peroxide-promoted radical addition of unsaturated ester to aldehyde and subsequent topologically favored cyclization greatly simplified the synthesis. [ABSTRACT FROM AUTHOR]
- Subjects :
- *MONOTERPENES
*TERPENES
*HYDROCARBONS
*LIPIDS
*PEONIES
Subjects
Details
- Language :
- English
- ISSN :
- 00223263
- Volume :
- 72
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- Journal of Organic Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 25496393
- Full Text :
- https://doi.org/10.1021/jo0701278