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Trapping of inhibitor-induced conformational changes in the erythrocyte membrane anion exchanger....

Authors :
Xiao-Bo Tang
Casey, Joseph R.
Source :
Biochemistry. 11/02/99, Vol. 38 Issue 44, p14565. 8p. 3 Diagrams, 1 Chart, 3 Graphs.
Publication Year :
1999

Abstract

Examines changes in the regions of AE1, a chloride/bicarbonate anion exchanger of erythrocyte membrane during the binding of 4,4'-dinitrostilbene-2,2'-disulfonate (DNDS). Effect of DNDS on AE1 transport during biotin maleimide labeling; Effects of biotinylation mutant reductions; Substrate and DNDS binding regions of AE1.

Details

Language :
English
ISSN :
00062960
Volume :
38
Issue :
44
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
2542532
Full Text :
https://doi.org/10.1021/bi991524i