Back to Search
Start Over
Survival Chances of Mutants Starting With One Individual.
- Source :
-
Journal of Biological Physics . Dec2006, Vol. 32 Issue 6, p563-572. 10p. - Publication Year :
- 2006
-
Abstract
- A simple theoretical model of a Darwinian system (a periodic system with a multiplication phase and a selection phase) of entities (initial form of polymer strand, primary mutant and satellite mutants) is given. First case: one mutant is considered. One individual of the mutant appears in the multiplication phase of the first generation. The probabilities to find N individuals of the mutant $$W^{{\text{S}}}_{{\text{n}}} {\left( N \right)}$$ after the multiplication phase M of the n-th generation (with probability δ of an error in the replication, where all possible errors are fatal errors) and $$W^{{\text{S}}}_{{\text{n}}} {\left( N \right)}$$ after the following selection phase S (with probability β that one individual survives) are given iteratively. The evolutionary tree is evaluated. Averages from the distributions and the probability of extinction $$W^{{\text{S}}}_{\infty } {\left( 0 \right)}$$ are obtained. Second case: two mutants are considered (primary mutant and new form). One individual of the primary mutant appears in the multiplication phase of the first generation. The probabilities to find N p individuals of the primary mutant and N m individuals of the new form $$W^{{\text{M}}}_{{\text{n}}} {\left( {N_{{\text{p}}} ,\;N_{{\text{m}}} } \right)}$$ after the multiplication phase M of the n-th generation (probability ɛ of an error in the replication of the primary mutant giving the new form) and $$W^{{\text{S}}}_{{\text{n}}} {\left( {N_{{\text{p}}} ,\;N_{{\text{m}}} } \right)}$$ after the following selection phase S (probabilities β p and β m that one individual each of the primary mutant and of the new form survives) are given iteratively. Again the evolutionary tree is evaluated. Averages from the distributions are obtained. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00920606
- Volume :
- 32
- Issue :
- 6
- Database :
- Academic Search Index
- Journal :
- Journal of Biological Physics
- Publication Type :
- Academic Journal
- Accession number :
- 25277923
- Full Text :
- https://doi.org/10.1007/s10867-007-9036-1