A Heterogeneous PNA-Based SERS Method for DNA Detection.

Authors :: Fabris, Laura
Dante, Mark
Braun, Gary
Seung Joon Lee
Reich, Norbert O.
Moskovits, Martin
Thuc-Quyen Nguyen
Bazan, Guillermo C.
Source :: Journal of the American Chemical Society. 5/16/2007, Vol. 129 Issue 19, p6086-6087. 2p.
Publication Year :: 2007
Abstract: The article reports on a study concerning the utility of the surface-enhanced Raman spectroscopy (SERS) method for DNA Detection. In this study, researchers analysed how a single-stranded DNA (ssDNA) identification method takes advantage of surface-bound acids (PNAs) and an interplay of electrostatic interactions which produces SERS signals upon ssDNA/PNA hybridization.