Making the paper: Karen Liu.

The article focuses on the technique used by Karen Liu in completing her study on mouse embryonic development. She felt that she needed new tools for her to study more precisely of her subject, she later joined the Crabtree laboratory. The laboratory had developed an 89-amino-acid tag, the FRB, of which when drug rapamycin blends to the tag, it results to the stabilization of protein. To test the method, they set up mice containing FRB tagged glycogen synthase kinase which had been a success.