Back to Search Start Over

Palladium-Catalyzed Aryl—Aryl Cross-Coupling Reaction Using ortho-Substituted Arylindium Reagents.

Authors :
Pena, Miguel A.
Sestelo, José Perez
Sarandeses, Luis A.
Source :
Journal of Organic Chemistry. 2/16/2007, Vol. 72 Issue 4, p1271-1275. 5p. 4 Charts.
Publication Year :
2007

Abstract

A range of biaryl compounds (aryl—aryl, aryl—heteroaryl, and heteroaryl—heteroaryl) can be efficiently prepared by a palladium-catalyzed cross-coupling reaction between ortho-substituted triarylindium reagents and aryl halides. The triarylindium reagents are prepared by directed ortho-lithiation and transmetallation to indium from the corresponding benzene derivatives using various directed metallation groups (DMGs). The reaction proceeds smoothly in high yields and short reaction times with high atom economy (the three aryl groups attached to indium are efficiently transferred). [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00223263
Volume :
72
Issue :
4
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
24095428
Full Text :
https://doi.org/10.1021/jo062148s