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FTMS and TOF/TOF mass spectrometry in concert: Identifying peptides with high reliability using matrix prespotted MALDI target plates

Authors :
Dekker, Lennard J.
Burgers, Peter C.
Gűzel, Coşkun
Luider, Theo M.
Source :
Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Feb2007, Vol. 847 Issue 1, p62-64. 3p.
Publication Year :
2007

Abstract

Abstract: In this paper we describe a combination of the mass spectrometric techniques MALDI–TOF/TOF and MALDI–FTMS to identify proteins in complex samples using prespotted MALDI target plates. By this procedure accurate FTMS mass measurements and TOF/TOF data are obtained from the same spot. We have found that this combination of techniques leads to more reliable identification of peptides. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
15700232
Volume :
847
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences
Publication Type :
Academic Journal
Accession number :
23948952
Full Text :
https://doi.org/10.1016/j.jchromb.2006.08.031