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Value of lung biopsy in pulmonary diseases in children.
- Source :
-
Journal of Indian Association of Pediatric Surgeons . Oct-Dec2006, Vol. 11 Issue 4, p234-238. 5p. - Publication Year :
- 2006
-
Abstract
- Purpose: Open lung biopsy (OLB) is claimed to be a sensitive tool for the diagnosis of interstitial lung disease. It is reported to be associated with significant morbidity and mortality. Aim: Evaluate whether lung biopsy helped us to make a specific diagnosis, it had resulted in change in therapy and assessment of its morbidity and mortality. Materials and Methods: This was a retrospective analysis of 91 lung biopsies performed in 83 patients between January 2000 and December 2003. These children were allocated to three groups: a. Primary pulmonary pathology (22), b. Immunocompromised (49) i. Primary immunodeficiency (10), ii. Postchemotherapy and BMT (39), c. Pulmonary metastases from solid tumors (20) Results: A specific diagnosis was reached in 87/91 children (95%), but this resulted in a change in therapy (excluding lung meet) in only 23/71 (32%). It is lower in those postchemo/BMT 8/39 (20.6%). Postoperative morbidity occurred in 11/91 (12%) but procedure-related morbidity was only (3.2%). Death within a month of the biopsy occurred in six children (6.5%), with one (1.1%) procedure-related. Conclusion: 1. OLB is a safe procedure at our institution. 2. OLB is a sensitive tool to determine the specific cause of pulmonary infiltrate. 3. Change in therapy expected to be only in 32% of patients and even lower in postchemotherapy and BMT children [ABSTRACT FROM AUTHOR]
- Subjects :
- *LUNG biopsy
*INTERSTITIAL lung diseases
*DIAGNOSIS
*CHILDREN
*BIOPSY
Subjects
Details
- Language :
- English
- ISSN :
- 09719261
- Volume :
- 11
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Journal of Indian Association of Pediatric Surgeons
- Publication Type :
- Academic Journal
- Accession number :
- 23757966
- Full Text :
- https://doi.org/10.4103/0971-9261.29608