Silencing of TGF-beta signalling by the pseudoreceptor BAMBI.

Authors :: Onichtchouk, Darya
Chen, Te-Guang
Dosch, Roland
Gawantka, Volker
Delius, Hajo
Massague, Joan
Niehrs, Christof
Source :: Nature. 9/30/1999, Vol. 401 Issue 6752, p480. 6p. 16 Color Photographs, 9 Diagrams, 13 Graphs.
Publication Year :: 1999
Abstract: Presents research on cell growth regulation and differentiation. Members of the transforming growth factor-beta (TGF-beta) super family, which are vital for regulating growth and differentiation; Cloning of a transmembrane protein, BAMBI, which is related to TGF-beta family type 1 receptors, but lacks an intracellular kinase domain; Coexpression of BAMBI with the ventralizing morphogen BMP4 during Xenopus embryogenesis.