Design and evaluation of the tandem target for a simultaneous production of [11C]CH4 and [18F]-fluoride

Abstract: The tandem target for a simultaneous production of [11C]CH4 and [18F]-fluoride has been designed and evaluated. A separate recovery system has been applied for a simultaneous collection of [11C]CH4 and [18F]-fluoride after a bombardment. The [11C]CH4 target was placed in front, and the [18F]-fluoride target was posted successively. An aluminum grid was employed between the two target cavities to improve the burst pressure of the titanium foil during an irradiation. It was demonstrated that a useful amount of [11C]CH4 and [18F]-fluoride can be produced simultaneously by this newly designed system. [Copyright &y& Elsevier]