Highly Enantioselective Recognition of Dicarboxylic Acid Substrates by the Control of Nonlinear Responses.

The article discusses the high enantioselective recognition of dicarboxylic acid substrates by the control of nonlinear sigmoidal responses. An analogous compound of cerium(IV) bis(porphyrinato) double-decker complex that exhibits positive homotropic allostery on binding cyclohexane-(1R,2R)-dicarboxylic acid (RR-CHDA), could recognize three equivalents of RR-CHDA via seven hydrogen bonds without significant conformational changes.