Back to Search
Start Over
ProteinParser—A community based tool for the generation of a detailed protein consensus and FASTA output
- Source :
-
Computer Methods & Programs in Biomedicine . Jan2007, Vol. 85 Issue 1, p69-76. 8p. - Publication Year :
- 2007
-
Abstract
- Abstract: Comparison of bioinformatic data is a common application in the life sciences and beyond. In this communication, a novel Java based software tool, ProteinParser, is outlined. This software tool calculates a detailed consensus, or most common, amino acid at a given position in an aligned protein set, whilst also generating a full consensus protein FASTA output. A second application of this software tool, computing a consensus amino acid given a tolerance threshold, is also demonstrated. The phytase and the common bacterial β-lactamase proteins are analysed as ‘proof of concept’ examples. Consensus proteins, as generated by ProteinParser, are regularly utilised in the selection of residues for protein stabilisation mutagenesis; however, this widely applicable software tool will find many alternative applications in areas such as protein homology modelling. [Copyright &y& Elsevier]
- Subjects :
- *BIOINFORMATICS
*JAVA programming language
*COMPUTER software
*GENETIC mutation
Subjects
Details
- Language :
- English
- ISSN :
- 01692607
- Volume :
- 85
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Computer Methods & Programs in Biomedicine
- Publication Type :
- Academic Journal
- Accession number :
- 23279343
- Full Text :
- https://doi.org/10.1016/j.cmpb.2006.09.015