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Strategies for developing vaccines against H5N1 influenza A viruses
- Source :
-
Trends in Molecular Medicine . Nov2006, Vol. 12 Issue 11, p506-514. 9p. - Publication Year :
- 2006
-
Abstract
- Recent outbreaks of highly pathogenic avian influenza A virus (H5N1 subtype) infections in poultry and humans (through direct contact with infected birds) have raised concerns that a new influenza pandemic might occur in the near future. Effective vaccines against H5N1 virus are, therefore, urgently needed. Reverse-genetics-based inactivated vaccines have been prepared according to World Health Organization (WHO) recommendations and are now undergoing clinical evaluation in several countries. Here, we review the current strategies for the development of H5N1 influenza vaccines, and future directions for vaccine development. [Copyright &y& Elsevier]
- Subjects :
- *AVIAN influenza
*INFLUENZA vaccines
*EPIDEMICS
*DRUG development
Subjects
Details
- Language :
- English
- ISSN :
- 14714914
- Volume :
- 12
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Trends in Molecular Medicine
- Publication Type :
- Academic Journal
- Accession number :
- 22941081
- Full Text :
- https://doi.org/10.1016/j.molmed.2006.09.003