Baclofen decreases the reinforcing effects of alcohol in alcohol-preferring rats.

Source :: DATA: The Brown University Digest of Addiction Theory & Application. Nov2006, Vol. 25 Issue 11, p5-6. 2p.
Publication Year :: 2006
Abstract: The article focuses on a study which states that the reinforcing properties of alcohol and sucrose in a breed of alcohol-preferring rats was decreased by pretreatment with baclofen dose-dependently. The study was conducted in Italy by researcher Paola Maccioni. Pretreatment with baclofen resulted in a marked reduction of sucrose-reinforced responding. With the highest dose of baclofen, alcohol-reinforced responding was reduced by about 80% in rats.

Language :: English
ISSN :: 10406328
Volume :: 25
Issue :: 11
Database :: Academic Search Index
Journal :: DATA: The Brown University Digest of Addiction Theory & Application
Publication Type :: Periodical
Accession number :: 22924067

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