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Genomics meets HIV-1.
- Source :
-
Nature Reviews Microbiology . Nov2006, Vol. 4 Issue 11, p865-873. 9p. 1 Diagram, 1 Chart, 2 Graphs. - Publication Year :
- 2006
-
Abstract
- Genomics is now a core element in the effort to develop a vaccine against HIV-1. Thanks to unprecedented progress in high-throughput genotyping and sequencing, in knowledge about genetic variation in humans, and in evolutionary genomics, it is finally possible to systematically search the genome for common genetic variants that influence the human response to HIV-1. The identification of such variants would help to determine which aspects of the response to the virus are the most promising targets for intervention. However, a key obstacle to progress remains the scarcity of appropriate human cohorts available for genomic research. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GENOMICS
*VACCINES
*GENOMES
*HIV infections
*AIDS
*HLA histocompatibility antigens
Subjects
Details
- Language :
- English
- ISSN :
- 17401526
- Volume :
- 4
- Issue :
- 11
- Database :
- Academic Search Index
- Journal :
- Nature Reviews Microbiology
- Publication Type :
- Academic Journal
- Accession number :
- 22741333
- Full Text :
- https://doi.org/10.1038/nrmicro1532