G03 Aliamides modulate skin mast cell degranulation in dogs and cats.

The article focuses on a study that analyzes the mechanism of action of aliamides in dogs and cats. In this study the aliamide parent molecule palmitoylethanolamide, and its topically-active congener adelmidrol, was tested on cutaneous mast cells of dogs and cats. Densitometric analysis performed on skin biopsies of allergic cats and canine skin wounds showed an increase in the staining intensity of cutaneous mast cells suggesting that aliamides are effective in decreasing degranulation.