Effect of Fluticasone Propionate/Salmeterol on Lung Hyperinflation and Exercise Endurance in COPD.

The article examines the effect of fluticasone propionate/salmeterol (FSC 250/50) on lung hyperinflation and exercise endurance in chronic obstructive pulmonary disease (COPD) patients. Predose and postdose spirometry, plethysmography and constant-load cycle cardiopulmonary exercises test evaluations have been compared. It was found that FSC 250/50 significantly reduced postdose functional residual capacity and increased inspiratory capacity compared with placebo.