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A Noncanonical Path to Mechanism of Action

Authors :
Peterson, Randall T.
Source :
Chemistry & Biology. Sep2006, Vol. 13 Issue 9, p924-926. 3p.
Publication Year :
2006

Abstract

Improved methods for discovering small-molecule mechanisms of action are needed. In this issue of Chemistry & Biology, Zhang et al. make clever use of the zebrafish to study the mechanism of the angiogenesis inhibitor fumagillin and reveal that it targets the noncanonical Wnt pathway. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
10745521
Volume :
13
Issue :
9
Database :
Academic Search Index
Journal :
Chemistry & Biology
Publication Type :
Academic Journal
Accession number :
22395707
Full Text :
https://doi.org/10.1016/j.chembiol.2006.09.002