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Identification of a new reaction intermediate in the oxidation of methylamine dehydrogenase by...

Authors :
Zhenyu Zhu
Davidson, Victor L.
Source :
Biochemistry. 04/13/99, Vol. 38 Issue 15, p4862. 6p. 2 Diagrams, 1 Chart, 8 Graphs.
Publication Year :
1999

Abstract

Identifies a novel reaction intermediate in the oxidation of methylamine dehydrogenase by amicyanin. Stoichiometric formation of the N-semiquinone in vitro; Electron transfer to amicyanin; Release of ammonia from tryptophan tryptophylquinone (TTQ); Initiation of nucleophilic attack of the N-quinone TTQ by the methylamine molecule.

Details

Language :
English
ISSN :
00062960
Volume :
38
Issue :
15
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
2212358
Full Text :
https://doi.org/10.1021/bi982939r