Announcement of the Editor-in-Chief.

As decided in July 2005 we continue to publish once a year (in July) the names of the authors and the titles of the two most read (by Internet) Research Papers and Reviews published in Cell. Mol. Life Sci. the previous year. Thus we have the pleasure to provide you with the results of 2005. M. Columbaro a, C. Capanni b, E. Mattioli a, G. Novelli c, V. K. Parnaik d, S. Squarzoni b, N. M. Maraldi a, b and G. Lattanzi b E. Garcia-Garcia a, S. Gil b, K. Andrieux a, D. Desmaële c, V. Nicolas d, F. Taran e, D. Georgin e, J. P. Andreux b, F. Roux f and P. Couvreur a C. R. McCudden, M. D. Hains, R. J. Kimple, D. P. Siderovski and F. S. Willard M. P. Mayer and B. Bukau [ABSTRACT FROM AUTHOR]