Studies toward the construction of substituted piperidine-2-ones and pyridine-2-ones from Baylis–Hillman adducts: discovery of a facile synthesis of 5-methyl-4-oxo-6-aryl-3-aza-bicyclo[3.1.0]hexane-1-carboxylates

Abstract: Studies toward the construction of functionalized piperidone derivatives from derivatives of Baylis–Hillman adducts are described. Interestingly the 6-oxo-4-aryl-piperidine-3-carboxylates generated during the study serve as precursor for the facile synthesis of 4-oxo-6-aryl-3-aza-bicyclo[3.1.0]hexane-1-carboxylates. [Copyright &y& Elsevier]