Incidence of Opportunistic and Other Infections in HIV-Infected Children in the HAART Era.

This article focuses on an estimation of the incidence of opportunistic and other infections in human immunodeficiency virus-infected (HIV-infected) infants, children, and adolescents to compare rates in the era of highly active antiretroviral therapy (HAART) to those of the pre-HAART era and test for trends over time in the HAART era. Methods of the study, main outcome measures, and results are detailed. Opportunistic infections and other related infections are infrequent in children in the HAART era and rates of infection continue to be lower than those reported in the pre-HAART era. In order to assess the longer-term effect of HAART on the occurrence of opportunistic and other related infections in children, continued surveillance is necessary.