Effect of microwave heating on Ullmann-type heterocycle-aryl ether synthesis using chloro-heterocycles

Authors :: D’Angelo, Noel D.
Peterson, Joseph J.
Booker, Shon K.
Fellows, Ingrid
Dominguez, Celia
Hungate, Randall
Reider, Paul J.
Kim, Tae-Seong
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jul2006, Vol. 47 Issue 29, p5045-5048. 4p.
Publication Year :: 2006
Abstract: Abstract: Ullmann ether synthesis was conducted on a variety of chloro-heterocycles with different phenols using optimized conditions involving copper powder and cesium carbonate. On many substrates, microwave heating afforded higher yields in significantly shorter reaction times compared to conventional heating conditions. These findings provide a facile method for aryl ether synthesis from chloropyridines, chloroquinolines, and chlorobenzothiazoles. [Copyright &y& Elsevier]

Subjects :: *DIRECT energy conversion
*ELECTRIC heating
*ORGANIC compounds
*AROMATIC compounds

Language :: English
ISSN :: 00404039
Volume :: 47
Issue :: 29
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 21187508
Full Text :: https://doi.org/10.1016/j.tetlet.2006.05.103

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