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Markedly enhancing lipase-catalyzed synthesis of nucleoside drugs’ ester by using a mixture system containing organic solvents and ionic liquid
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Jul2006, Vol. 16 Issue 14, p3769-3771. 3p. - Publication Year :
- 2006
-
Abstract
- Abstract: Eightfold higher yields and three times faster reaction rates were achieved by means of using a mixture solvent system composed of 90% acetone and 10% [BMIM]BF4 in the lipase-catalyzed regioselective synthesis of polymerizable ester of nucleoside drugs. [Copyright &y& Elsevier]
- Subjects :
- *ORGANIC compounds
*ORGANIC solvents
*SOLUTION (Chemistry)
*CHEMICAL kinetics
Subjects
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 16
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 21049392
- Full Text :
- https://doi.org/10.1016/j.bmcl.2006.04.054