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Gastro-oesophageal reflux symptoms and health-related quality of life in the adult general population – the Kalixanda study.
- Source :
-
Alimentary Pharmacology & Therapeutics . Jun2006, Vol. 23 Issue 12, p1725-1733. 9p. 2 Charts, 3 Graphs. - Publication Year :
- 2006
-
Abstract
- Background The impact of gastro-oesophageal reflux symptoms on health-related quality of life in the general population is poorly characterized. Aim To identify the frequency of troublesome reflux symptoms associated with impaired health-related quality of life in the general population. Methods A representative random sample of 3000 adult inhabitants of northern Sweden was surveyed using the validated Abdominal Symptom Questionnaire (response rate 74%). In total, 1001 random responders were endoscoped and assessed using the Short Form-36 Health Survey. Results Complete data were obtained for 999 subjects: 6% reported reflux symptoms (heartburn and/or regurgitation) daily, 14% weekly and 20% less than weekly during the previous 3 months. Compared with no reflux symptoms, a clinically relevant impairment of health-related quality of life (≥5 points and P < 0.05) was seen in all eight Short Form-36 dimensions for daily symptoms, in five dimensions for weekly symptoms and in one dimension for less than weekly symptoms. There were no meaningful differences in Short Form-36 scores between subjects with and without oesophagitis. Conclusions Most aspects of health-related quality of life were impaired in individuals with daily or weekly reflux symptoms. Troublesome reflux symptoms at least weekly may identify gastro-oesophageal reflux disease. [ABSTRACT FROM AUTHOR]
- Subjects :
- *GASTROESOPHAGEAL reflux
*HEALTH
*NUTRITION
*MEDICINE
Subjects
Details
- Language :
- English
- ISSN :
- 02692813
- Volume :
- 23
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Alimentary Pharmacology & Therapeutics
- Publication Type :
- Academic Journal
- Accession number :
- 21023463
- Full Text :
- https://doi.org/10.1111/j.1365-2036.2006.02952.x