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Enhanced simultaneous production of mycelia and intracellular polysaccharide in submerged cultivation of Cordyceps jiangxiensis using desirability functions
- Source :
-
Process Biochemistry . Aug2006, Vol. 41 Issue 8, p1887-1893. 7p. - Publication Year :
- 2006
-
Abstract
- Abstract: The effects of medium composition and fermentation parameters on simultaneous production of mycelia and intracellular polysaccharide by medicinal mushroom, Cordyceps jiangxiensis were investigated in shake-flask cultures using desirability functions. The optimal conditions were obtained via the associated desirability as follows: 40g/l of molasses glycerol, 5g/l of peanut steep meal, 6g/l of yeast extract, 1g/l of KH2PO4, 0.5g/l of ZnCl2, 0.5g/l of MgSO4, initial pH at 6, cultivation temperature at 28°C, 200ml of medium working volume in a 500ml flask and 5% (v/v) of inoculum size. Under these conditions, the production titer of mycelia and intracellular polysaccharide reached 24.5 and 8.9g/l, respectively, after a 9-day submerged cultivation. The use of desirability functions was proved effective in optimizing multi-response fermentation processes and it is readily applicable to other fermentation systems. [Copyright &y& Elsevier]
- Subjects :
- *FERMENTATION
*INDUSTRIAL microbiology
*BIOCHEMICAL engineering
*MYCELIUM
Subjects
Details
- Language :
- English
- ISSN :
- 13595113
- Volume :
- 41
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Process Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 20963906
- Full Text :
- https://doi.org/10.1016/j.procbio.2006.03.031