Inhibition of Preadipocyte Differentiation by Germacranolides from Calea urticifolia in 3T3-L1 Cells.

The article examines the effects of germacranolides isolated from Calea urticifolia on adipocytic differentiation of 3T3-L1 cells. It observes no inhibitory activity against cell proliferation and binding activity to protein. The effect shows germacranolides as the specific inhibitors of pre-adipocyte differentiation. A graph depicts the effect of compound 3 on 3T3-L1 cells proliferation.