Directed DNA Metallization.

This article presents information on the DNA metallization procedures that was developed in order to increase the conductivity of subsequent DNA nanostructures. Since the construction of nanodevices requires the preparation of long DNA double-stranded scaffolds from several to hundreds of nanometers in length, the author's surmised that selective aldehyde labeling could be achieved via an enzymatic method. The article informs that the direct incorporation of an aldehyde-modified triphosphate analogue provides a more expeditious route toward aldehyde-modified DNA. Their enzymatic incorporation provided mixed results.