Reductive opening of glycal derived highly functionalized 2,3-epoxy-1-iodides with zinc dust: an efficient method for the synthesis of acyclic long chain polyhydroxylated terminal alkenic alcohols

Authors :: Reddy, L. Vijaya Raghava
Sagar, Ram
Shaw, Arun K.
Source :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2006, Vol. 47 Issue 11, p1753-1756. 4p.
Publication Year :: 2006
Abstract: Abstract: The synthesis of densely functionalized acyclic long chain terminal alkenic alcohols was achieved by reductive opening of glycal derived 2,3-epoxy-1-iodides, with commercial zinc dust alone in a short reaction time with excellent yields involving a simple reaction procedure and easy work-up. A mechanism involving an organometallic intermediate is proposed. [Copyright &y& Elsevier]

Language :: English
ISSN :: 00404039
Volume :: 47
Issue :: 11
Database :: Academic Search Index
Journal :: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :: Academic Journal
Accession number :: 19686738
Full Text :: https://doi.org/10.1016/j.tetlet.2006.01.043

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