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Retinal vessel dilation following repletion of vitamin A deficiency
- Source :
-
Experimental Eye Research . Feb2006, Vol. 82 Issue 2, p349-350. 2p. - Publication Year :
- 2006
-
Abstract
- Abstract: We hypothesized that because depletion of vitamin A blocks the initiation of phototransduction, such inhibition of functional activation should lead to decrease retinal metabolism and perfusion. In a case study of a vitamin A-depleted patient, we found that retinal vessel diameters, a surrogate measure of retinal perfusion, increased in concert with the restitution of electroretinographic function following vitamin A supplementation. When normalized to conditions after treatment, the relative magnitude of study parameters at presentation were: scotopic electroretinography B-wave amplitude 1.2%, photopic electroretrinography B-wave amplitude 23%, retinal vein diameter 88%, retinal artery diameter 94%. These observations support that activation of the visual process results in increased retinal metabolism and perfusion. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 00144835
- Volume :
- 82
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Experimental Eye Research
- Publication Type :
- Academic Journal
- Accession number :
- 19533505
- Full Text :
- https://doi.org/10.1016/j.exer.2005.10.001