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Estrogen receptor ligands. Part 14: Application of novel antagonist side chains to existing platforms

Authors :
Blizzard, Timothy A.
Morgan, Jerry D.
Chan, Wanda
Birzin, Elizabeth T.
Pai, Lee-Yuh
Hayes, Edward C.
DaSilva, Carolyn A.
Mosley, Ralph T.
Yang, Yi Tien
Rohrer, Susan P.
DiNinno, Frank
Hammond, Milton L.
Source :
Bioorganic & Medicinal Chemistry Letters. Dec2005, Vol. 15 Issue 23, p5124-5128. 5p.
Publication Year :
2005

Abstract

Abstract: Two novel side chains which had previously been found to enhance antagonist activity in the dihydrobenzoxathiin SERM series were applied to three existing platforms. The novel side chains did not improve the antagonist activity of the existing platforms. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0960894X
Volume :
15
Issue :
23
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
18950816
Full Text :
https://doi.org/10.1016/j.bmcl.2005.08.084