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Control of Autoimmune Diabetes in NOD Mice by GAD Expression or Suppression in Beta Cells.
- Source :
-
Science . 5/14/1999, Vol. 284 Issue 5417, p1183-1187. 5p. 18 Color Photographs, 7 Black and White Photographs, 2 Diagrams, 11 Graphs. - Publication Year :
- 1999
-
Abstract
- Presents research which described the role of glutamic acid decarboxylase (GAD) in the development of diabetes in mice. Effects of beta cell-specific suppression of GAD expression; Impact of persistent GAD expression; Effects of complete suppression of beta cell GAD expression; GAD expression in the development of autoimmune diabetes in mice; Possible therapeutic value of GAD modulation.
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 284
- Issue :
- 5417
- Database :
- Academic Search Index
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- 1874815
- Full Text :
- https://doi.org/10.1126/science.284.5417.1183